Arginine and glucose metabolism in a strain of Streptococcus pyogenes.

McIlwain (Biochem J. (London), 40, 67, 1946) reported that glutamine, arginine, and urea stimulate glycolysis in resting cells of the hemolytic streptococcus. We have observed an analogous phenomenon in cell-free preparations of a single strain of Streptococcus pyogenes (S23). Our cell-free extracts were prepared by grinding the washed cells from 1,600 ml of an 18 hour broth culture of a nonmucoid variant of strain